ニツタ コウサク
Nitta Kosaku
新田 孝作 所属 その他 その他 職種 非常勤嘱託 |
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論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Transcriptional factors, Mafs and their biological roles. |
掲載誌名 | 正式名:World journal of diabetes 略 称:World J Diabetes ISSNコード:1948-9358(Electronic)1948-9358(Linking) |
巻・号・頁 | 6(1),pp.175-83 |
著者・共著者 | Tsuchiya Mariko†, Misaka Ryoichi, Nitta Kosaku, Tsuchiya Ken |
発行年月 | 2015/02 |
概要 | The Maf family of transcription factors is characterized by a typical bZip structure; these transcription factors act as important regulators of the development and differentiation of many organs and tissues, including the kidney. The Maf family consists of two subgroups that are characterized according to their structure: large Maf transcription factors and small Maf transcription factors. The large Maf subgroup consists of four proteins, designated as MAFA, MAFB, c-MAF and neural retina-specific leucine zipper. In particular, MAFA is a distinct molecule that has been attracting the attention of researchers because it acts as a strong transactivator of insulin, suggesting that Maf transcription factors are likely to be involved in systemic energy homeostasis. In this review, we focused on the regulation of glucose/energy balance by Maf transcription factors in various organs. |
DOI | 10.4239/wjd.v6.i1.175 |
文献番号 | 25685288 |