ニツタ　コウサク   Nitta Kosaku   新田　孝作    所属   その他 その他    職種   非常勤嘱託
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Relation of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and left atrial volume index to left ventricular function in chronic hemodialysis patients.
掲載誌名	正式名：Heart and vessels 略　 称：Heart Vessels ISSNコード：1615-2573(Electronic)0910-8327(Linking)
巻・号・頁	26(4),pp.421-7
著者・共著者	Yamazaki Mayuko†, Ogawa Tetsuya, Tamei Noriko, Ando Yoshitaka, Nitta Kosaku
担当区分	最終著者
発行年月	2011/07
概要	Cardiovascular disease is the major cause of death in hemodialysis (HD) patients. We investigated the relation of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and left atrial volume index (LAVi) to left ventricular function in chronic HD patients. A total of 117 patients were enrolled as subjects (74 men and 43 women). Echocardiography was performed to evaluate the left atrial volume index (LAVi) and left ventricular mass index (LVMI). Diastolic left ventricular function was estimated as E/E' by tissue Doppler imaging with cardiac ultrasonography. Serum NT-proBNP was measured at the time of echocardiographic measurements. Multiple regression analysis showed that LAVi (F = 24.372, p<0.0001) and E/E' (F = 23.473, p<0.0116) were significant predictors for serum NT-proBNP levels, and LVMI (F = 46.807, p<0.0001) was a best predictor for LAVi among associated factors. These findings suggest that serum NT-proBNP and LAVi are both good biomarkers for predicting the LV remodeling in chronic HD patients.
DOI	10.1007/s00380-010-0066-4
文献番号	21127887