Nobuhisa Hagiwara
Department Other, Other Position |
|
Article types | Original article |
Language | English |
Peer review | Non peer reviewed |
Title | Utility of dobutamine stress echocardiography in aortic valve regurgitation and reduced left ventricular function. |
Journal | Formal name:Echocardiography (Mount Kisco, N.Y.) Abbreviation:Echocardiography ISSN code:15408175/07422822 |
Domestic / Foregin | Foregin |
Volume, Issue, Page | 39(4),pp.599-605 |
Author and coauthor | Saito Chihiro†, Arai Kotaro, Ashihara Kyomi, Niinami Hiroshi, Hagiwara Nobuhisa |
Publication date | 2022/04 |
Summary | OBJECTIVE:Predictors for post-operative reverse remodeling in patients with severe aortic regurgitation (AR) and reduced left ventricular ejection fraction (LVEF) are unknown. We performed low-dose dobutamine stress echocardiography (DSE) in patients with severe AR and reduced LVEF to evaluate the relationship between contractile reserve (CR) and reverse remodeling after surgery.METHODS:In 31 patients with chronic severe AR and reduced LVEF (LVEF < 50%), we performed pre-operative DSE, assessed CR, and examined whether changes in preoperative DSE were associated with improvement of post-operative LVEF after aortic valve surgery.RESULTS:The pre-operative echocardiographic findings were as follows: left ventricular (LV) end-diastolic dimension: 67 ± 10 mm, LV end-systolic dimension: 52 ± 13 mm, and LVEF: 42 ± 8%. All patients underwent aortic valve surgery. Patients with pre-operative LVEF of ≥45% exhibited a significant increase in LVEF; however, patients with pre-operative LVEF of <45% showed no significant change. When we examined the results of DSE performed in patients with pre-operative LVEF of <45%, ΔLVEF of ≥6% (with CR) during DSE was related to an improvement in post-operative LVEF; ΔLVEF of ≥6% during DSE predicted an improvement in post-operative LVEF, with sensitivity 100%; specificity 78%; and area under curve (AUC) .92.CONCLUSIONS:DSE might be a helpful tool for predicting post-operative reverse remodeling in patients with severe AR and moderately reduced LVEF. |
DOI | 10.1111/echo.15334 |
PMID | 35294054 |