菅野　仁    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Professor (Fixed Term)
Article types	Original article
Language	English
Peer review	Peer reviewed
Title	Genotypic analysis using a Y-chromosome-specific probe following bone marrow transplantation.
Journal	Formal name：American journal of hematology Abbreviation：Am J Hematol ISSN code：0361-8609(Print)0361-8609(Linking)
Volume, Issue, Page	27(1),pp.30-3
Author and coauthor	Morisaki H, Morisaki T, Nakahori Y, Ogura H, Kanno H, Tani K, Kodo H, Fujii H, Asano S, Miwa S
Publication date	1988/01
Summary	To monitor successful engraftment after bone marrow transplantation, we performed Southern hybridization analysis or dotblot analysis of DNA in a set of sex-mismatched cases using a Y-chromosome-specific DNA probe (pHY10). This method was extremely sensitive and rapid for checking which cells contain the Y-chromosome. Using this probe, analysis of cells from peripheral blood and bone marrow after transplantation demonstrated the usefulness of confirming engraftment of donor cells and of detecting mixed lymphohematopoietic chimerism.
Document No.	3281450