カンノ ヒトシ
  菅野 仁
   所属   医学部 医学科(東京女子医科大学病院)
   職種   特任教授
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Genotypic analysis using a Y-chromosome-specific probe following bone marrow transplantation.
掲載誌名 正式名:American journal of hematology
略  称:Am J Hematol
ISSNコード:0361-8609(Print)0361-8609(Linking)
巻・号・頁 27(1),pp.30-3
著者・共著者 Morisaki H, Morisaki T, Nakahori Y, Ogura H, Kanno H, Tani K, Kodo H, Fujii H, Asano S, Miwa S
発行年月 1988/01
概要 To monitor successful engraftment after bone marrow transplantation, we performed Southern hybridization analysis or dotblot analysis of DNA in a set of sex-mismatched cases using a Y-chromosome-specific DNA probe (pHY10). This method was extremely sensitive and rapid for checking which cells contain the Y-chromosome. Using this probe, analysis of cells from peripheral blood and bone marrow after transplantation demonstrated the usefulness of confirming engraftment of donor cells and of detecting mixed lymphohematopoietic chimerism.
文献番号 3281450