シミズ　キヨウコ   SHIMIZU Kyoko   清水　京子    所属   その他 その他    職種   非常勤嘱託
論文種別	総説
言語種別	英語
査読の有無	査読なし
表題	Evidence-based clinical practice guidelines for chronic pancreatitis 2021.
掲載誌名	正式名：Journal of gastroenterology 略　 称：J Gastroenterol ISSNコード：14355922/09441174
掲載区分	国内
巻・号・頁	57(10),pp.709-724
著者・共著者	SHIMIZU Kyoko†, ITO Tetsuhide, IRISAWA Atsushi, OHTSUKA Takao, OHARA Hirotaka, KANNO Atsushi, KIDA Mitsuhiro, SAKAGAMI Junichi, SATA Naohiro, TAKEYAMA Yoshifumi, TAHARA Junko, HIROTA Morihisa, FUJIMORI Nao, MASAMUNE Atsushi, MOCHIDA Satoshi, ENOMOTO Nobuyuki, SHIMOSEGAWA Tooru, KOIKE Kazuhiko
担当区分	筆頭著者
発行年月	2022/10
概要	BACKGROUND:Chronic pancreatitis (CP) is defined according to the recently proposed mechanistic definition as a pathological fibro-inflammatory syndrome of the pancreas in individuals with genetic, environmental, and/or other risk factors who develop persistent pathological responses to parenchymal injury or stress.METHODS:The clinical practice guidelines for CP in Japan were revised in 2021 based on the 2019 Japanese clinical diagnostic criteria for CP, which incorporate the concept of a pathogenic fibro-inflammatory syndrome in the pancreas. In this third edition, clinical questions are reclassified into clinical questions, background questions, and future research questions.RESULTS:Based on analysis of newly accumulated evidence, the strength of evidence and recommendations for each clinical question is described in terms of treatment selection, lifestyle guidance, pain control, treatment of exocrine and endocrine insufficiency, and treatment of complications. A flowchart outlining indications, treatment selection, and policies for cases in which treatment is ineffective is provided. For pain control, pharmacological treatment and the indications and timing for endoscopic and surgical treatment have been updated in the revised edition.CONCLUSIONS:These updated guidelines provide clinicians with useful information to assist in the diagnosis and treatment of CP.
DOI	10.1007/s00535-022-01911-6
PMID	35994093