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HATTORI Motoshi
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Professor |
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| Article types | Other |
| Language | English |
| Peer review | Peer reviewed |
| Title | Clinical guides for atypical hemolytic uremic syndrome in Japan. |
| Journal | Formal name：Pediatrics international : official journal of the Japan Pediatric Society Abbreviation：Pediatr Int ISSN code：(1442-200X)1328-8067(Linking) |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 58(7),pp.549-55 |
| Author and coauthor | Kato Hideki†, Nangaku Masaomi, Hataya Hiroshi, Sawai Toshihiro, Ashida Akira, Fujimaru Rika, Hidaka Yoshihiko, Kaname Shinya, Maruyama Shoichi, Yasuda Takashi, Yoshida Yoko, Ito Shuichi, Hattori Motoshi, Miyakawa Yoshitaka, Fujimura Yoshihiro, Okada Hirokazu, Kagami Shoji, |
| Publication date | 2016/07 |
| Summary | Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. In 2013, we developed diagnostic criteria to enable early diagnosis and timely initiation of appropriate treatment for aHUS. Recent clinical and molecular findings have resulted in several proposed classifications and definitions of thrombotic microangiopathy and aHUS. Based on recent advances in this field and the emerging international consensus to exclude secondary TMAs from the definition of aHUS, we have redefined aHUS and proposed diagnostic algorithms, differential diagnosis, and therapeutic strategies for aHUS. |
| DOI | 10.1111/ped.13044 |
| PMID | 27460397 |