イワドウ カズヒロ   IWADOH Kazuhiro
  岩藤 和広
   所属   医学部 医学科(東京女子医科大学病院)
   職種   非常勤講師
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Successful Long-term Graft Survival of a Renal Transplantation Patient with Wiskott-Aldrich Syndrome
掲載誌名 正式名:Internal medicine (Tokyo, Japan)
略  称:Intern Med
ISSNコード:09182918/13497235
掲載区分国内
巻・号・頁 55(13),pp.1761-1763
著者・共著者 KAI KOTARO†, Ogawa Yuichi, MIKI Katsuyuki, IWADOH Kazuhiro, Sannomiya Akihiro, MURAKAMI Toru, Koyama Ichiro, Kitajima Kumiko, Nakajima Ichiro, Fuchinoue Shohei
発行年月 2016
概要 Wiskott-Aldrich syndrome, a rare X-linked hereditary syndrome, is characterized by immunodeficiency, thrombocytopenia, and eczema. The underlying T-cell defect renders renal transplantation and immunosuppressive treatments uncertain. The present case exhibited the mild clinical manifestation, regarded as X-linked thrombocytopenia. He successfully underwent a living-donor ABO-compatible renal transplantation and splenectomy in 2002, and thereafter experiencing no severe rejection, serious infection, or malignancy for more than 10 years. Though IgA nephropathy was detected 8 months after transplantation, the patient's renal function and proteinuria were stable without any treatment. The present case showed a successful long-term graft survival and the importance of splenectomy added to renal transplantation.
DOI 10.2169/internalmedicine.55.6337