中溝　宗永    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Professor (Fixed Term)
Article types	Original article
Language	English
Peer review	Peer reviewed
Title	Surgical treatment for pulmonary metastases of squamous cell carcinoma of the head and neck.
Journal	Formal name：American journal of otolaryngology Abbreviation：Am J Otolaryngol ISSN code：01960709/01960709
Domestic / Foregin	Foregin
Volume, Issue, Page	18(6),pp.391-395
Author and coauthor	NIBU Kenichi, NAKAGAWA Ken, KAMATA Shin-etsu, KAWABATA Kazuyoshi, NAKAMIZO Munenaga, NIGAURI Tomohiko, HOKI Katsufumi
Publication date	1998
Summary	PURPOSE:As locoregional control of head and neck cancer has improved, distant metastases have become increasingly common problems.PATIENTS AND METHODS:To determine the role of surgical treatment, we reviewed 32 patients with squamous cell carcinoma (SCC) of the head and neck who underwent thoracotomy for pulmonary metastases.RESULTS:The overall 5-year survival rate was 32%. The 5-year survival rate of the patients with SCC of the oral cavity was significantly poorer than that of the patients with other primary site (15.4% v 45.2%; P = .01). In the patients with single nodule, extent of the tumor was a significant prognostic factor (P = .007). Mediastinal lymph node involvement (P = .004) and pleural invasion (P = .04) also correlated with survival.CONCLUSION:TNM classification of the primary tumor did not have an impact on survival in this study. Further studies of a large series should be performed to determine the indications and modalities of the surgical treatment for pulmonary metastases of the SCC of head and neck.
DOI	10.1016/s0196-0709(97)90059-4
PMID	9395015