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中溝 宗永
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Professor (Fixed Term) |
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| Article types | Case report |
| Language | English |
| Peer review | Peer reviewed |
| Title | Descending necrotizing mediastinitis associated with Lactobacillus plantarum. |
| Journal | Formal name：BMC infectious diseases Abbreviation：BMC Infect Dis ISSN code：14712334/14712334 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 13,pp.398 |
| Author and coauthor | Nei Takahito, Inai Shunta, Mikami Iwao, Sato Akira, Okamoto Junichi, Yokoshima Kazuhiko, Nakamizo Munenaga, Haraguchi Shuji, Sonobe Kazunari, Saito Ryoichi |
| Publication date | 2013/08 |
| Summary | BACKGROUND:Descending necrotizing mediastinitis (DNM), a severe infection with a high fatality rate, develops in mediastinal spaces due mainly to deep cervical abscesses. The majority of causative microbes of DNM are Streptococci and oral anaerobes. DNM associated with Lactobacillus-infection is rather rare.CASE PRESENTATION:A 69-year-old male with an unremarkable past medical history was referred to our hospital for surgical resection of advanced laryngeal cancer. Full examination revealed a neck abscess and DNM with a background of untreated diabetes mellitus. Initially, he was treated with meropenem. However, Lactobacillus plantarum was isolated from surgical drainage of a mediastinal abscess. Despite using antibiotics capable of eradicating all isolates with susceptibilities not differing significantly from those of the neck and mediastinal abscesses, we attributed DNM to the L. plantarum detected only in the mediastinal abscess. After DNM treatment, he underwent total pharyngolaryngectomy with bilateral neck dissection followed by reconstruction using free jejunum. He was discharged fully recovered.CONCLUSION:We concluded that L. plantarum as the sole cause of the mediastinal abscess in the present case cannot be ruled out. As the number of immunocompromised patients increases, we should be cautious regarding this "familiar" microbe. |
| DOI | 10.1186/1471-2334-13-398 |
| PMID | 23987907 |