ナカミゾ　ムネナガ   中溝　宗永    所属   医学部 医学科（東京女子医科大学病院）    職種   特任教授
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Surgical management of tongue cancer during pregnancy.
掲載誌名	正式名：Auris, Nasus, lLrynx 略　 称：ANL ISSNコード：18791476/03858146
掲載区分	国外
巻・号・頁	39(4),pp.428-430
著者・共著者	YOKOSHIMA Kazuhiko, NAKAMIZO Munenaga, SAKANUSHI Atsuko, OZU Ryu-ichiro, YAMAGUCHI Satoshi, TONE Yuko, INAI Shunta, MURAKAMI Ryousuke, OHKUBO Kimihiro
担当区分	2nd著者
発行年月	2012/08
概要	There are ethical dilemmas in managing head and neck cancers during pregnancy. Diagnostic and treatment modalities need to be carefully determined. We herein describe 3 cases of tongue cancer during pregnancy. The details of the management would contribute to the daily practices for head and neck cancers. All three patients were Japanese female patients, two of them were 29 years old and one was 26 years old. All patients were admitted to the Nippon Medical School Hospital during pregnancy, complaining of oral pain and/or discomfort. Case 1 was diagnosed as tongue cancer stage T3N0M0, however, the tumor was superficial and controllable by partial glossectomy. Case 2 was stage T2N0M0 with deep invasion with ulcer, and the hemi-glossectomy with neck dissection and the reconstruction was thought to be the standard modality. However, she underwent partial glossectomy in order to reduce the stress of the fetus. Case 3 could not be diagnosed on admission by biopsy and she underwent partial glossectomy after delivery. In case 3, the pathological diagnosis was pT1 tongue cancer. In case 1 and case 3, the patient and baby were healthy. In case 2, however, the patient died of recurrence at the primary site. In decision making of the strategy, the most important factors are not only oncological evaluation but also ethical and emotional factors.
DOI	10.1016/j.anl.2011.08.003
PMID	21889278