中溝 宗永
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor (Fixed Term)
Article types Case report
Language English
Peer review Peer reviewed
Title Three cases of carcinoma of the hypopharynx developing as metachronous second primary cancers after total laryngectomy with radiotherapy for carcinoma of the larynx.
Journal Formal name:Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
Abbreviation:J Nippon Med Sch
ISSN code:13473409/13454676
Domestic / ForeginForegin
Volume, Issue, Page 78(4),pp.261-266
Author and coauthor YOKOSHIMA Kazuhiko, NAKAMIZO Munenaga, KOKAWA Takayuki, INAI Shunta, SAKANUSHI Atsuko, SAITO Yukiko, OHKUBO Kimihiro
Authorship 2nd author
Publication date 2011
Summary We describe 3 cases of metachronous hypopharyngeal cancer developing after laryngeal cancer had been treated with both radiotherapy and total laryngectomy. All 3 patients were men, 2 were 89 years old, and 1 was 65 years old. All patients had undergone total laryngectomy and radiotherapy for cancer for the glottis more than 20 years earlier. All patients underwent total hypopharyngectomy with jejunal free flap reconstruction. Surgery was complicated by scars from previous cancer treatment, and highly sophisticated surgical skills are needed, especially for preparing the recipient vessels. The postoperative period was largely uneventful and without fatal complications, however, 2 of the 3 patients died of distant metastasis 22 months and 31 months after surgery.
DOI 10.1272/jnms.78.261
PMID 21869562