Ichiba Shingo    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Professor
Article types	Case report
Language	English
Peer review	Peer reviewed
Title	Successful extracorporeal life support for life-threatening hypercapnia with bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation.
Journal	Formal name：Acta medica Okayama Abbreviation：Acta Med Okayama ISSN code：0386300X/0386300X
Domestic / Foregin	Domestic
Volume, Issue, Page	65(6),pp.403-406
Author and coauthor	Waseda Koichi, Tanimoto Yasushi, Ichiba Shingo, Miyahara Nobuaki, Murakami Toshi, Ochi Nobuaki, Terado Michihisa, Nagano Osamu, Maeda Yoshinobu, Kanehiro Arihiko, Ujike Yoshihito, Tanimoto Mitsune
Publication date	2011/12
Summary	Bronchiolitis obliterans (BO) is a disease with a poor prognosis, and a key factor that limits long-term survival after allogeneic hematopoietic stem cell transplantation (HSCT). We here report a case of a 31-year woman with acute lymphatic leukemia, which was treated by chemotherapy and HSCT, and consequently developed BO 2 years after HSCT. A non-tuberculous mycobacterial infection occurred and showed gradual exacerbation. She started taking anti-mycobacterial drugs, but lost appetite, felt tired and finally lost consciousness one month after beginning medication. Arterial blood gas revealed marked hypercapnia. Using extracorporeal life support (ECLS), the carbon dioxide concentration was reduced and her consciousness recovered. To our knowledge, this is the first case in which ECLS was successfully used for hypercapnia in a patient with BO.
DOI	10.18926/AMO/47266
PMID	22189481