Ichiba Shingo
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor
Article types Case report
Language English
Peer review Peer reviewed
Title Fulminant eosinophilic myocarditis associated with visceral larva migrans caused by Toxocara canis infection.
Journal Formal name:Circulation journal : official journal of the Japanese Circulation Society
Abbreviation:Circ J
ISSN code:13469843/13469843
Domestic / ForeginDomestic
Volume, Issue, Page 73(7),pp.1344-1348
Author and coauthor Enko Kenki, Tada Takeshi, Ohgo Keiko O, Nagase Satoshi, Nakamura Kazufumi, Ohta Kei, Ichiba Shingo, Ujike Yoshihito, Nawa Yukifumi, Maruyama Haruhiko, Ohe Tohru, Kusano Kengo F
Publication date 2009/07
Summary A 19-year-old man was transferred to hospital because of myocarditis with cardiogenic shock. Echocardiography showed a left ventricular ejection fraction of 23.8% and an intermediate amount of pericardial effusion. The patient immediately received an intra-aortic balloon pump and percutaneous cardiopulmonary support. Right ventricular endomyocardial biopsy was performed in the acute phase and showed extensive eosinophilic inflammatory cell infiltration, severe interstitial edema and moderate myocardial necrosis. High-dose corticosteroids were administered. Because the patient's antibody titer against Toxocara canis was high and his symptoms had appeared after eating raw deer meat, the diagnosis was fulminant eosinophilic myocarditis caused by a hypersensitivity reaction to visceral larval migrans. After starting high-dose corticosteroids, the ejection fraction dramatically improved, the eosinophilia decreased and the patient made a full recovery.
DOI 10.1253/circj.cj-08-0334
PMID 19122304