SAKAI Shuji
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor and Division head
Article types Other
Language English
Peer review Non peer reviewed
Title 11C-methionine PET/CT findings in benign brain disease.
Journal Formal name:Japanese journal of radiology
Abbreviation:Jpn J Radiol
ISSN code:(1867-108X)1867-1071(Linking)
Domestic / ForeginDomestic
Volume, Issue, Page 35(6),pp.279-288
Author and coauthor Nakajima Reiko, Kimura Ken, abe Koichiro, Sakai Shuji, 坂井 修二
Authorship Last author
Publication date 2017/06
Summary 11C-methionine (MET) is one of the most commonly used positron emission tomography (PET) tracers for evaluation of malignant brain tumor, with MET-PET being a sensitive technique for visualization of primary and recurrent malignant brain tumors. However, previous reports have demonstrated MET uptake in lesions associated with benign brain diseases. These diseases usually show an increase in MET uptake similar to that of malignant tumors. This pitfall in MET-PET image interpretation is important not only for nuclear medicine professionals, but also for radiologists. In this review, we demonstrate the imaging characteristics of MET uptake in benign brain disease, and recommend physician interpretation of imaging findings and disease characteristics for optimal patient management. Benign uptake must be identified to prevent misdiagnosis and unnecessary surgical operations.
DOI 10.1007/s11604-017-0638-7
PMID 28421396