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Kikuchi Ken
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Professor |
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| Article types | Case report |
| Language | English |
| Peer review | Peer reviewed |
| Title | Breakthrough Candida guilliermondii (Meyerozyma guilliermondii) fungemia after cord blood transplantation for extranodal NK-cell lymphoma with azole prophylaxis. |
| Journal | Formal name：Transplant infectious disease : an official journal of the Transplantation Society Abbreviation：Transpl Infect Dis ISSN code：(1399-3062)1398-2273(Linking) |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | pp.e12922 |
| Author and coauthor | Nakazawa Hideyuki, Nishina Sayaka, Senoo Yasushi, Sakai Hitoshi, Ito Toshiro, Kikuchi Ken, Ishida Fumihiro |
| Publication date | 2018/05 |
| Summary | Fluconazole (FLCZ) is an azole antifungal agent and it has shown excellent clinical activities in suppressing fungemia with Candida albicans after hematopoietic stem cell transplantation. Increased administration of prophylactic FLCZ seems to have given rise to the relatively higher incidence of more resistant Candida non-albicans infection. We present a case with a rare breakthrough fungemia with C. guilliermondii after cord blood transplantation for Extranodal NK cell Lymphoma, nasal type (ENKL), during antifungal prophylaxis with FLCZ. High level of caution is needed for the breakthrough, especially after long- term azole administration. |
| DOI | 10.1111/tid.12922 |
| PMID | 29797683 |