KIKUCHI Ken
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor
Article types Case report
Language English
Peer review Peer reviewed
Title Breakthrough Candida guilliermondii (Meyerozyma guilliermondii) fungemia after cord blood transplantation for extranodal NK-cell lymphoma with azole prophylaxis.
Journal Formal name:Transplant infectious disease : an official journal of the Transplantation Society
Abbreviation:Transpl Infect Dis
ISSN code:(1399-3062)1398-2273(Linking)
Domestic / ForeginForegin
Volume, Issue, Page pp.e12922
Author and coauthor Nakazawa Hideyuki, Nishina Sayaka, Senoo Yasushi, Sakai Hitoshi, Ito Toshiro, Kikuchi Ken, Ishida Fumihiro
Publication date 2018/05
Summary Fluconazole (FLCZ) is an azole antifungal agent and it has shown excellent clinical activities in suppressing fungemia with Candida albicans after hematopoietic stem cell transplantation. Increased administration of prophylactic FLCZ seems to have given rise to the relatively higher incidence of more resistant Candida non-albicans infection. We present a case with a rare breakthrough fungemia with C. guilliermondii after cord blood transplantation for Extranodal NK cell Lymphoma, nasal type (ENKL), during antifungal prophylaxis with FLCZ. High level of caution is needed for the breakthrough, especially after long- term azole administration.
DOI 10.1111/tid.12922
PMID 29797683