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Kikuchi Ken
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Professor |
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| Article types | Original article |
| Language | English |
| Peer review | Peer reviewed |
| Title | Rapid Acquisition of Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus: Role of Hypermutation and Homologous Recombination. |
| Journal | Formal name：PloS one Abbreviation：PLoS One ISSN code：(1932-6203)1932-6203(Linking) |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 11(5),pp.e0155512 |
| Author and coauthor | Iguchi Shigekazu, Mizutani Tomonori, Hiramatsu Keiichi, Kikuchi Ken |
| Authorship | Last author,Corresponding author |
| Publication date | 2016 |
| Summary | Hypermutation and homologous recombination of the ribosomal RNA genes, including 23S rRNA genes, appear not to have been sources of the accelerated acquisition of linezolid resistance observed in our clinical case. Increased frequency of short sequence recombination may have resulted from a recQ variant in the infecting organism. |
| DOI | 10.1371/journal.pone.0155512 |
| PMID | 27182700 |