キクチ ケン   Kikuchi Ken
  菊池 賢
   所属   医学部 医学科(東京女子医科大学病院)
   職種   教授
論文種別 原著
言語種別 英語
査読の有無 査読有り
表題 Rapid Acquisition of Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus: Role of Hypermutation and Homologous Recombination.
掲載誌名 正式名:PloS one
略  称:PLoS One
ISSNコード:(1932-6203)1932-6203(Linking)
掲載区分国外
巻・号・頁 11(5),e0155512頁
著者・共著者 Iguchi Shigekazu, Mizutani Tomonori, Hiramatsu Keiichi, Kikuchi Ken
発行年月 2016
概要 Hypermutation and homologous recombination of the ribosomal RNA genes, including 23S rRNA genes, appear not to have been sources of the accelerated acquisition of linezolid resistance observed in our clinical case. Increased frequency of short sequence recombination may have resulted from a recQ variant in the infecting organism.
DOI 10.1371/journal.pone.0155512
PMID 27182700