キクチ ケン   Kikuchi Ken
  菊池 賢
   所属   医学部 医学科(東京女子医科大学病院)
   職種   教授
論文種別 症例報告
言語種別 英語
査読の有無 査読有り
表題 Catheter-related blood stream infection caused by Dermacoccus barathri, representing the first case of Dermacoccus infection in humans.
掲載誌名 正式名:Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
略  称:J Infect Chemother
ISSNコード:(1437-7780)1341-321X(Linking)
掲載区分国内
巻・号・頁 21(8),613-6頁
著者・共著者 Takahashi Nobuhiro, Shinjoh Masayoshi, Tomita Hirofumi, Fujino Akihiro, Sugita Kayoko, Katohno Yasuhiro, Kuroda Tatsuo, Kikuchi Ken
発行年月 2015/08
概要 A 7-year-old boy undergoing home parenteral nutrition with totally implantable central venous access device for chronic intestinal pseudo-obstruction experienced repeated episodes of fever with a temperature above 39.0 C despite the antibiotic treatment. The fever was considered to be catheter-related blood stream infections, as no other etiology could be justified. Repeated blood culture tests revealed negative after 1-week incubation, whereas some samples of blood collected from the central venous catheter yielded positive and gram-positive rods were detected. These bacteria were detected repeatedly, then the central venous access device was removed with consideration for the possibility of this bacteria being a pathogen. Thereafter, the fever did not recur and the blood culture tests were negative. The causative agent was identified as Dermacoccus barathri based on the 16S rRNA gene sequence and phylogenetic analysis of 6118 bp concatenated sequences of 4 housekeeping genes. Genus Dermacoccus are one form of Actinomycetes isolated from human skin and water, but human infection with Dermacoccus spp. has not been previously reported and the pathogenicity of the bacteria remains unclear. To our knowledge, this is the first reported case of Dermacoccus infection in humans.
DOI 10.1016/j.jiac.2015.04.007
PMID 26044303