キクチ ケン   Kikuchi Ken
  菊池 賢
   所属   医学部 医学科(東京女子医科大学病院)
   職種   教授
論文種別 原著
言語種別 英語
査読の有無 査読有り
表題 The clinical utility of a near patient care rapid microarray-based diagnostic test for influenza and respiratory syncytial virus infections in the pediatric setting.
掲載誌名 正式名:Diagnostic microbiology and infectious disease
略  称:Diagn Microbiol Infect Dis
ISSNコード:(1879-0070)0732-8893(Linking)
掲載区分国外
巻・号・頁 78(4),363-7頁
著者・共著者 Nakao Akihiro, Hisata Ken, Matsunaga Nobuaki, Fujimori Makoto, Yoshikawa Naomi, Komatsu Mitsutaka, Kikuchi Ken, Takahashi Hiroshi, Shimizu Toshiaki
発行年月 2014/04
概要 We evaluated the potential clinical utility of an automated near patient molecular assay Verigene Respiratory Virus Plus (RV+) and rapid immunochromatographic antigen tests (RIAT) in the pediatric setting for diagnosis of influenza and respiratory syncytial virus infections when testing was performed by the pediatrician seeing the patient. Overall, with respect to influenza virus, sensitivity and specificity for RIAT were 70.8% and 100%, respectively, compared to 100% and 96.2%, respectively, for RV+. For respiratory syncytial virus, sensitivity and specificity for RIAT were 78.9% and 100%, respectively, compared to 100% and 100%, respectively, for RV+. When RIAT and RV+ sensitivity for influenza virus was compared based on the time the patient presented after onset of fever, the sensitivity of RIAT at 6 hours was 37.5% compared to 100% for RV+. At 12 hours, RIAT improved to 60.9%. This study confirms the clinical utility of RV+ in the pediatric setting.
DOI 10.1016/j.diagmicrobio.2013.11.005
PMID 24582577