Tsuyoshi Shiga
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Visiting Professor
Article types Original article
Language English
Peer review Peer reviewed
Title Role of desethylamiodarone in the anticoagulant effect of concurrent amiodarone and warfarin therapy.
Journal Formal name:Journal of cardiovascular pharmacology and therapeutics
Abbreviation:J Cardiovasc Pharmacol Ther
ISSN code:(1074-2484)1074-2484(Linking)
Volume, Issue, Page 6(4),pp.363-367
Author and coauthor Naganuma M†, Shiga T*, Nishikata K, Tsuchiya T, Kasanuki H, Fujii E
Authorship 2nd author,Corresponding author
Publication date 2001/10
Summary It was suggested that inhibition of CYP2C9 by desethylamiodarone, the active metabolite of amiodarone, plays an important role in the interaction of warfarin and amiodarone.
PMID 11907638