佐藤 加代子
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position  
Article types Original article
Language English
Peer review Non peer reviewed
Title Functional profile of activated dendritic cells in unstable atherosclerotic plaque.
Journal Formal name:Basic research in cardiology
Abbreviation:Basic Res Cardiol
ISSN code:03008428
Domestic / ForeginForegin
Volume, Issue, Page 102(2),pp.123-32
Author and coauthor Erbel Christian†, Sato Kayoko, Meyer Frederic B, Kopecky Stephen L, Frye Robert L, Goronzy Jörg J, Weyand Cornelia M
Publication date 2007/03
Summary Activated and fully mature DC are represented in the inflammatory infiltrate characteristic for unstable carotid and coronary atheroma. Such DC produce chemokines, and thus can regulate the cell traffic into the lesion. Through the expression of the costimulatory ligand CD86, plaque-residing DC can augment T-cell stimulation and provide optimal stimulation conditions for T lymphocytes, resembling the microenvironment in organized lymphoid tissues.
DOI 10.1007/s00395-006-0636-x
PMID 17136419