NIINAMI Hiroshi
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor and Division head
Article types Original article
Language English
Peer review Non peer reviewed
Title The mid-term outcomes of aortic root replacement after surgical repair for CHD.
Journal Formal name:Cardiology in the young
Abbreviation:Cardiol Young
ISSN code:14671107/10479511
Domestic / ForeginForegin
Volume, Issue, Page pp.1-9
Author and coauthor Furuta Akihisa†, Shinkawa Takeshi, Yoshizawa Saeko, Okugi Satoshi, Niinami Hiroshi
Publication date 2023/11
Summary OBJECTIVE:The purpose of this study is to assess the mid-term outcomes of aortic root replacement after repair of CHDs.METHOD:This is a single-institutional retrospective, cohort study with consecutive patients undergoing aortic root replacement after surgical repair of CHDs between 1999 and 2022. Operative indications included aortic root dilatation with/without aortic insufficiency, sinus of Valsalva rupture, or aortic dissection involving the root.RESULTS:Forty-four patients (36 male and 8 female) were enrolled. Mean age at the root replacement was 36.6 ± 11.9 years. The most frequent primary diagnosis was congenital aortic stenosis (n = 10) and ventricular septal defect (n = 10). Mean time from the surgical repair to aortic root replacement was 26.6 ± 13.0 years. Operative indications were aortic root enlargement with or without aortic valve aetiology (n = 40), sinus of Valsalva rupture (n = 2), and aortic dissection (n = 2). Forty-two patients underwent valve-replacing aortic root replacement, and two patients underwent valve-sparing, with 40 concomitant procedures. The median follow-up was 3.5 (1.3-7.6) years. There were one early and five late mortalities and five cardiovascular-related reoperations. Actuarial survival at 5-10 years after root replacement was 81.0 ± 6.6%. The cumulative incidence of cardiovascular-related reoperation and aortic root or valve-related reoperation at 5 years after root replacement was 11.9% and 5.6%, respectively.CONCLUSION:The early and mid-term outcomes of aortic root replacement for patients with a history of repair of CHDs were favourable in terms of survival and aortic root or valve-related reoperation.
DOI 10.1017/S1047951123003864
PMID 37955043