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春田 昭二
Department School of Medicine(Yachiyo Medical Center), School of Medicine Position Clinical Professor |
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| Article types | Original article |
| Language | English |
| Peer review | Peer reviewed |
| Title | Use of fondaparinux for thromboprophylaxis in an unfractionated heparin-intolerant pregnant woman with thrombotic predisposition. |
| Journal | Formal name：The journal of obstetrics and gynaecology research Abbreviation：J Obstet Gynaecol Res ISSN code：14470756/13418076 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 43(5),pp.943-945 |
| Author and coauthor | Haruta S† |
| Publication date | 2017/05 |
| Summary | A 34-year-old primigravida who had undergone thrombectomy for deep venous thrombosis (DVT) in her leg and exhibited low protein S activity, indicating predisposition to thrombosis, developed DVT of the leg. No pulmonary embolism was detected. After anticoagulant therapy with unfractionated heparin was discontinued because of liver dysfunction, danaparoid treatment was administered in hospital. The patient had a normal delivery after 39 weeks' gestation with no recurrence of thrombosis. During her second pregnancy four years later, she gave herself fondaparinux injections. She delivered normally after 38 weeks' gestation without experiencing DVT. Fondaparinux may be a useful anticoagulant for heparin-intolerant pregnant women. |
| DOI | 10.1111/jog.13302 |
| PMID | 28437037 |