ハルタ シヨウジ
  春田 昭二
   所属   医学部 医学科(附属八千代医療センター)
   職種   准教授
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Use of fondaparinux for thromboprophylaxis in an unfractionated heparin-intolerant pregnant woman with thrombotic predisposition.
掲載誌名 正式名:The journal of obstetrics and gynaecology research
略  称:J Obstet Gynaecol Res
ISSNコード:14470756/13418076
掲載区分国外
巻・号・頁 43(5),pp.943-945
著者・共著者 Haruta S†
発行年月 2017/05
概要 A 34-year-old primigravida who had undergone thrombectomy for deep venous thrombosis (DVT) in her leg and exhibited low protein S activity, indicating predisposition to thrombosis, developed DVT of the leg. No pulmonary embolism was detected. After anticoagulant therapy with unfractionated heparin was discontinued because of liver dysfunction, danaparoid treatment was administered in hospital. The patient had a normal delivery after 39 weeks' gestation with no recurrence of thrombosis. During her second pregnancy four years later, she gave herself fondaparinux injections. She delivered normally after 38 weeks' gestation without experiencing DVT. Fondaparinux may be a useful anticoagulant for heparin-intolerant pregnant women.
DOI 10.1111/jog.13302
PMID 28437037