MURAGAKI Yoshihiro
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Visiting Professor
Article types Original article
Language English
Peer review Peer reviewed
Title Global post-marketing safety surveillance of Tumor Treating Fields (TTFields) in patients with high-grade glioma in clinical practice.
Journal Formal name:Journal of neuro-oncology
Abbreviation:J Neurooncol
ISSN code:15737373/0167594X
Domestic / ForeginForegin
Volume, Issue, Page 148(30),pp.489-500
Author and coauthor SHI Shi Wenyin†*, BLUMENTHAL Deborah T, OBERHEIM-BUSH Nancy Ann, KEBIR Sied, LUKAS Rimas V, MURAGAKI Yoshihiro, ZHU Jay-Jiguang, GLAS Martin
Publication date 2020/07
Summary INTRODUCTION:Tumor Treating Fields (TTFields; antimitotic treatment) delivers low-intensity, intermediate-frequency, alternating electric fields through skin-applied transducer arrays. TTFields (200 kHz) was FDA-approved in glioblastoma (GBM), based on the phase 3 EF-11 (recurrent GBM, rGBM) and EF-14 (newly diagnosed GBM, ndGBM) trials. The most common TTFields-related adverse event (AE) in both trials was array-associated skin irritation. We now report on TTFields-related AEs in the real-world, clinical practice setting
DOI 10.1007/s11060-020-03540-6
PMID 32535723