MURAGAKI Yoshihiro
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Visiting Professor |
|
Article types | Original article |
Language | English |
Peer review | Peer reviewed |
Title | Correlation between fractional anisotropy changes in the targeted ventral intermediate nucleus and clinical outcome after transcranial MR-guided focused ultrasound thalamotomy for essential tremor: results of a pilot study |
Journal | Formal name:Journal of neurosurgery Abbreviation:J Neurosurg ISSN code:00223085/19330693 |
Domestic / Foregin | Foregin |
Volume, Issue, Page | 132(2),pp.568-573 |
Author and coauthor | HORI Hiroki†, YAMAGUCHI Toshio, KONISHI Yoshiyuki, TAIRA Takaomi, MURAGAKI Yoshihiro* |
Authorship | Last author,Corresponding author |
Publication date | 2019/02 |
Summary | CLINICAL ARTICLE
OBJECTIVE This study evaluated changes of fractional anisotropy (FA) in the ventral intermediate nucleus (VIM) of the thalamus after transcranial MR-guided focused ultrasound (TcMRgFUS) thalamotomy and their associations with clinical outcome. METHODS Clinical and radiological data of 12 patients with medically refractory essential tremor (mean age 76.5 years) who underwent TcMRgFUS thalamotomy with VIM targeting were analyzed retrospectively. The Clinical Rating Scale for Tremor (CRST) score was calculated before and at 1 year after treatment. Measurements of the relative FA (rFA) values, defined as ratio of the FA value in the targeted VIM to the FA value in the contralateral VIM, were performed before thalamotomy, and 1 day and 1 year thereafter. |
DOI | 10.3171/2018.10.JNS18993 |
PMID | 30771772 |