MURAGAKI Yoshihiro
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Visiting Professor
Article types Case report
Language English
Peer review Peer reviewed
Title Role of a Promoter Mutation in the Telomerase Reverse Transcriptase Gene in Malignant Transformation of Pleomorphic Xanthoastrocytoma.
Journal Formal name:World neurosurgery
Abbreviation:World Neurosurg
ISSN code:(1878-8769)1878-8750(Linking)
Domestic / ForeginForegin
Volume, Issue, Page 126,pp.624-630
Author and coauthor HOSONO Junji†, NITTA Masayuki, MASUI Kenta, MARUYAMA Takashi, KOMORI Takashi, YOKOO Hideaki, SAITO Taiichi, MURAGAKI Yoshihiro, KAWAMATA Takakazu
Publication date 2019/06
Summary It was suggested that TERT promotor mutations may contribute to the malignant transformation of PXA; the mechanism of this mutation is unknown, but it may have been caused by SRS. Therefore, improvident use of radiation should be avoided to prevent the malignant transformation of PXA.
DOI 10.1016/j.wneu.2018.12.095
PMID 30599247