ムラガキ ヨシヒロ   MURAGAKI Yoshihiro
  村垣 善浩
   所属   医学部 医学科(東京女子医科大学病院)
   職種   客員教授
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Phase I/IIa trial of autologous formalin-fixed tumor vaccine concomitant with fractionated radiotherapy for newly diagnosed glioblastoma
掲載誌名 正式名:Journal of Neurosurgery
略  称:J Neurosurg
ISSNコード:19330693
掲載区分国外
巻・号・頁 115(2),pp.248-255
著者・共著者 MURAGAKI Yoshihiro†, MARUYAMA Takashi, ISEKI Hiroshi, TANAKA Masahiko, SHINOHARA Chie, TAKAKURA Kintomo, TSUBOI Koji,YAMAMOTO Tetsuya, MATSUMURA Akira, MATSUTANI Masao, KARASAWA Katsuyuki,SHIMADA Katsunori, YAMAGUCHI Naohito, NAKAZATO Yoichi , SATO Keiki, UEMAE Youji, OHNO Tadao, OKADA Yoshikazu, HORI Tomokatsu
発行年月 2011/08
概要 The objective of the present study was analysis of results of the prospective clinical trial directed toward the evaluation of therapeutic efficacy of the administration of autologous formalin-fixed tumor vaccine (AFTV) concomitant with fractionated radiotherapy in cases of newly diagnosed glioblastoma multiforme.|Twenty-four patients were enrolled into the clinical trial, while 2 cases were excluded from the final analysis of results. The treatment protocol included aggressive tumor resection, fractionated radiotherapy up to a total dose of 60 Gy, and 3 concomitant courses of AFTV administered with an interval of one week at the late stage of irradiation.
DOI 10.3171/2011.4.jns10377
文献番号 21568657