所属 研究施設 研究施設 職種 教授
|表題||"Donut's Shape" Radiosurgical Treatment Planning for Large Cystic Metastatic Brain Tumors|
|掲載誌名||正式名：Minimally Invasive Neurosurgery|
略 称：Minim Invasive Neurosurg
|著者・共著者||Hayashi Motohiro†, Chernov Mikhail, Tamura Noriko, Tamura Manabu, Izawa Masahiro, Muragaki Yoshihiro, Iseki Hiroshi, Okada Yoshikazu|
Radiosurgical management of large cystic metastatic brain tumors represents a significant challenge. Nevertheless, modified dose planning has shown beneficial results in such cases.
METHOD AND RESULTS:
"Donut's shape" radiosurgical treatment planning is based on the chain-like application of multiple, small-sized isocenters for selective coverage of the contrast-enhancing tumor capsule and minimal irradiation of the central cystic area. Such an approach was used for the management of large cystic intracranial metastases, which were not accompanied by a significant mass effect and did not require immediate volume reduction. Treatment was done using Leksell Gamma Knife model C with automatic positioning system. The majority of treated lesions showed significant shrinkage after radiosurgery and no major complications were met.
Large cystic metastatic brain tumors may be successfully treated with gamma knife radiosurgery alone using the proposed "donut's shape" dose planning with coverage of the contrast-enhancing tumor capsule by multiple small-sized isocenters.