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SHIMIZU Yuko
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Professor |
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| Article types | Original article |
| Language | English |
| Peer review | Peer reviewed |
| Title | The MG-QOL15 Japanese version: validation and associations with clinical factors. |
| Journal | Formal name：Muscle & nerve Abbreviation：Muscle Nerve ISSN code：10974598/0148639X |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 46(2),pp.166-17３ |
| Author and coauthor | Masuda Masayuki, Utsugisawa Kimiaki, Suzuki Shigeaki, Nagane Yuriko, Kabasawa Chiaki, Suzuki Yasushi, Shimizu Yuko, Utsumi Hiroya, Fujihara Kazuo, Uchiyama Shinichiro, Suzuki Norihiro |
| Publication date | 2012/08 |
| Summary | INTRODUCTION:Our study aim was to produce a Japanese translation of the 15-item Myasthenia Gravis Quality-of-Life Scale (MG-QOL15), assess its reliability and validity, and examine clinical factors affecting self-perceived QOL in MG.METHODS:We evaluated 327 consecutive patients with MG seen at six neurological centers. All patients completed the Japanese version of the MG-QOL15 (MG-QOL15-J), the Beck Depression Inventory-second edition (BDI-II), and a generic health-related QOL questionnaire, the SF-36. Disease severity was determined according to the Myasthenia Gravis Foundation of America (MGFA) quantitative MG score and the MG composite.RESULTS:The MG-QOL15-J exhibited adequate internal reliability, test-retest repeatability, and concurrent validity with SF-36, disease severity, and known-patient groups categorized by MGFA post-intervention status. Multivariate analysis revealed severity, dose of oral corticosteroids, and BDI-II as independent factors negatively affecting QOL.CONCLUSION:The MG-QOL15-J is anticipated to be a valuable clinical measure of QOL in Japanese patients with MG. |
| DOI | 10.1002/mus.23398 |
| PMID | 22806364 |