SHIMIZU Yuko    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Professor
Article types	Original article
Language	English
Peer review	Peer reviewed
Title	Validation of the brief international cognitive assessment for multiple sclerosis in Japan
Journal	Formal name：Multiple sclerosis journal - experimental, translational and clinical. ISSN code：20552173
Domestic / Foregin	Foregin
Volume, Issue, Page	3(4),pp.2055217317748972
Author and coauthor	NIINO Masaaki, FUKAZAWA Toshiyuki, OKUNO Tatsusada, MORI Masahiro, SANJO Nobuo, OHASHI Takashi, FUKAURA Hiroaki, FUJIMORI Juichi, SHIMIZU Yuko, MIFUNE Nobuhiro, MIYAZAKi Yuusei, TAKAHASHI Eri, KIKUCHI Seiji, LANGDON Dawn, BENDICT HB Ralph, MATSUI Makoto
Publication date	2017/12
Summary	Background:The Brief International Cognitive Assessment for MS (BICAMS) is a practical battery for measuring cognitive function in multiple sclerosis (MS).Objectives:We aimed to validate a Japanese version of the BICAMS in patients with MS and healthy controls.Methods:The Symbol Digit Modalities Test (SDMT), the California Verbal Learning Test-Second Edition (CVLT2) and the Brief Visuospatial Memory Test Revised (BVMTR) were administered to 156 patients with MS and 126 healthy controls (HCs). The BICAMS was re-administered in a subset of 27 MS patients and 30 HCs.Results:The mean (±SD) raw scores in the MS and HC groups were as follows: SDMT: MS 47.9 ± 14.0, HC 61.0 ± 9.5; CVLT2: MS 48.6 ± 12.6, HC 55.7 ± 10.5; BVMTR: MS 23.5 ± 8.4, HC 28.3 ± 5.4, respectively, and significant differences were found between the two groups on all tests (p < 0.0001). Cohen's d values were 1.07, 0.60, and 0.67 in SDMT, CVLT2, and BVMTR, respectively. The test-retest reliability coefficients for each test were as follows: SDMT: r = 0.93; CVLT2: r = 0.82; and BVMTR: r = 0.77 (p < 0.0001).Conclusions:This study provides results that support the reliability and validity of the BICAMS in Japan.
DOI	10.1177/20552173177489723
PMID	29339837