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Nanke Yuki
Department School of Nursing, School of Nursing Position Professor |
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| Article types | Review article |
| Language | English |
| Peer review | Peer reviewed |
| Title | The Role of Th17 Cells in the Pathogenesis of Behcet's Disease. |
| Journal | Formal name：Journal of clinical medicine Abbreviation：J Clin Med ISSN code：(2077-0383)2077-0383(Linking) |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 6(7),pp.piiE74 |
| Author and coauthor | Nanke Yuki, Yago Toru, Kotake Shigeru |
| Publication date | 2017/07 |
| Summary | Behcet's disease (BD) is a polysymptomatic and recurrent systemic vasculitis with a chronic course and unknown cause. The pathogenesis of BD has not been fully elucidated; however, BD has been considered to be a typical Th1-mediated inflammatory disease, characterized by elevated levels of Th1 cytokines such as IFN-γ, IL-2, and TNF-α. Recently, some studies reported that Th17-associated cytokines were increased in BD; thus, Th17 cells and the IL17/IL23 pathway may play important roles in the pathogenesis of BD. In this chapter, we focus on the pathogenic role of Th17 cells in BD. |
| DOI | 10.3390/jcm6070074 |
| PMID | 28753995 |