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Nanke Yuki
Department School of Nursing, School of Nursing Position Professor |
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| Article types | Case report |
| Language | English |
| Peer review | Peer reviewed |
| Title | Case of Chlamydia-associated arthritis. |
| Journal | Formal name：Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology Abbreviation：Nihon Rinsho Meneki Gakkai Kaishi ISSN code：(1349-7413)0911-4300(Linking) |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 32(6),pp.511-4 |
| Author and coauthor | Nanke Yuki, Kobashigawa Tsuyoshi, Yago Toru, Ichikawa Naomi, Kamatani Naoyuki, Kotake Shigeru |
| Publication date | 2009/12 |
| Summary | We report a case of Chlamydia-associated arthritis in a 40-year-old man. The patient experienced four episodes of Chlamydia trachomatis urtethritis within a few years. During the present episode, polyarthritis developed a few days after Chlamydia trachomatis urethritis was noted. The patient was diagnosed as having Chlamydia-associated arthritis. Loxoprofen sodium and azithromycin were started. Antibiotics induced clinical improvement of urethritis, although arthritis persisted for 3 months. HLA-B27 was negative, but both HLA-B35 and B40 were positive. Thus, we speculate that positivity for both HLA-B35 and HLA-B40 contributed to the persistence of arthritis in this case. During the course, the levels of Th1, Th17 and regulatory T cells in the peripheral blood were increased on flowcytometry. Thus, we speculate that Th17 may play, at least in part, an important role of the pathogenesis in this case. |
| DOI | 10.2177/jsci.32.511 |
| PMID | 20046020 |