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Nanke Yuki
Department School of Nursing, School of Nursing Position Professor |
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| Article types | Case report |
| Language | English |
| Peer review | Peer reviewed |
| Title | Pancytopenia and colitis with Clostridium difficile in a rheumatoid arthritis patient taking methotrexate, antibiotics and non-steroidal anti-inflammatory drugs. |
| Journal | Formal name：Clinical rheumatology Abbreviation：Clin Rheumatol ISSN code：(0770-3198)0770-3198(Linking) |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 20(1),pp.73-5 |
| Author and coauthor | Nanke Y, Kotake S, Akama H, Tomii M, Kamatani N |
| Publication date | 2001 |
| Summary | Methotrexate (MTX) is widely used despite its side-effects. We describe a rheumatoid arthritis (RA) patient taking low-dose MTX who developed severe pancytopenia and colitis with Clostridium difficile after the administration of antibiotics for acute pyelonephritis. Our case suggests that low-dose MTX may seriously interact with antibiotics and that these side-effects should always be considered when RA patients are treated with MTX and antibiotics. |
| DOI | 10.1007/PL00011187 |
| PMID | 11254248 |