OHKI Takeshi
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Associate Professor
Article types Original article
Language English
Peer review Non peer reviewed
Title Lateral pelvic lymph nodes for rectal cancer: A review of diagnosis and management.
Journal Formal name:World journal of gastrointestinal oncology
Abbreviation:World J Gastrointest Oncol
ISSN code:19485204
Domestic / ForeginForegin
Volume, Issue, Page 13(10),pp.1412-1424
Author and coauthor OGAWA Shimpei†, ITABASHI Michio, INOUE Yuji, OHKI Takeshi, BAMBA Yoshiko, KOSHINO Kurodo, NAKAGAWA Ryosuke, TANI Kimitaka, AIHARA Hisako, KONDO Hiroka, YAMAGUCHI SHIGEKI, YAMAMOTO Masakazu]
Publication date 2021/10
Summary The current status and future prospects for diagnosis and treatment of lateral pelvic lymph node (LPLN) metastasis of rectal cancer are described in this review. Magnetic resonance imaging (MRI) is recommended for the diagnosis of LPLN metastasis. A LPLN-positive status on MRI is a strong risk factor for metastasis, and evaluation by MRI is important for deciding treatment strategy. LPLN dissection (LPLD) has an advantage of reducing recurrence in the lateral pelvis but also has a disadvantage of complications; therefore, LPLD may not be appropriate for cases that are less likely to have LPLN metastasis. Radiation therapy (RT) and chemoradiation therapy (CRT) have limited effects in cases with suspected LPLN metastasis, but a combination of preoperative CRT and LPLD may improve the treatment outcome. Thus, RT and CRT plus selective LPLD may be a rational strategy to omit unnecessary LPLD and produce a favorable treatment outcome.
DOI 10.4251/wjgo.v13.i10.1412
PMID 34721774