OHKI Takeshi
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Associate Professor
Article types Original article
Language English
Peer review Non peer reviewed
Title Esophageal tissue engineering: from bench to bedside.
Journal Formal name:Annals of the New York Academy of Sciences
Abbreviation:Ann N Y Acad Sci
ISSN code:(1749-6632)0077-8923(Linking)
Domestic / ForeginForegin
Volume, Issue, Page 1434(1),pp.156-163
Author and coauthor Arakelian Lousineh,KANAI Nobuo,Dua Kulwinde,Durand Marlène,Cattan Pierre,OHKI Takeshi
Authorship Last author,Corresponding author
Publication date 2018/12
Summary For various esophageal diseases, the search for alternative techniques for tissue repair has led to significant developments in basic and translational research in the field of tissue engineering. Applied to the esophagus, this concept is based on the in vitro combination of elements judged necessary for in vivo implantation to promote esophageal tissue remodeling. Different methods are currently being explored to develop substitutes using cells, scaffolds, or a combination of both, according to the severity of lesions to be treated. In this review, we discuss recent advances in (1) cell sheet technology for preventing stricture after extended esophageal mucosectomy and (2) full-thickness circumferential esophageal replacement using tissue-engineered substitutes.
DOI 10.1111/nyas.13951
PMID 30088660