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オオキ タケシ
OHKI Takeshi
大木 岳志 所属 医学部 医学科（東京女子医科大学病院） 職種 准教授 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読なし |
| 表題 | Esophageal tissue engineering: from bench to bedside. |
| 掲載誌名 | 正式名：Annals of the New York Academy of Sciences 略 称：Ann N Y Acad Sci ISSNコード：(1749-6632)0077-8923(Linking) |
| 掲載区分 | 国外 |
| 巻・号・頁 | 1434(1),pp.156-163 |
| 著者・共著者 | Arakelian Lousineh,KANAI Nobuo,Dua Kulwinde,Durand Marlène,Cattan Pierre,OHKI Takeshi |
| 担当区分 | 最終著者,責任著者 |
| 発行年月 | 2018/12 |
| 概要 | For various esophageal diseases, the search for alternative techniques for tissue repair has led to significant developments in basic and translational research in the field of tissue engineering. Applied to the esophagus, this concept is based on the in vitro combination of elements judged necessary for in vivo implantation to promote esophageal tissue remodeling. Different methods are currently being explored to develop substitutes using cells, scaffolds, or a combination of both, according to the severity of lesions to be treated. In this review, we discuss recent advances in (1) cell sheet technology for preventing stricture after extended esophageal mucosectomy and (2) full-thickness circumferential esophageal replacement using tissue-engineered substitutes. |
| DOI | 10.1111/nyas.13951 |
| PMID | 30088660 |