オカザキ　ケン   KEN OKAZAKI   岡崎　賢    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Minimum 10-year results of cementless total hip arthroplasty in patients with rheumatoid arthritis.
掲載誌名	正式名：Modern rheumatology 略　 称：Mod Rheumatol ISSNコード：14397609/14397595
掲載区分	国外
巻・号・頁	27(4),pp.598-604
著者・共著者	Haraguchi Akihisa, Nakashima Yasuharu, Miyahara Hisaaki, Esaki Yukio, Okazaki Ken, Fukushi Jun-Ichi, Hirata Go, Ikemura Satoshi, Kamura Satoshi, Sakuraba Koji, Fujimura Kenjiro, Akasaki Yukio, Yamada Hisakata
発行年月	2017/07
概要	OBJECTIVES:To retrospectively evaluate the long-term results of cementless total hip arthroplasty (THA) in patients with rheumatoid arthritis (RA) and postoperative patient mortality after THA.METHODS:This study included 191 hips in 149 RA patients who underwent cementless THA between 1998 and 2005. Mean age at surgery was 54.2 years, and mean follow-up was 12.6 years. Implant and patient survivorships were determined using the Kaplan-Meier method, and the associated influencing factors were determined.RESULTS:Implant survivals at 17 years were 99.5% for stems, 93.9% for cups, and 90.8% for liners. Among the liners used, THAs with highly cross-linked polyethylene showed better survivals compared with those with conventional polyethylene and alumina-bearing surface (93.4%, 90.9%, and 52.2%, respectively). A total of 64 deaths occurred; 45 patients died within 10 years and 19 patients died between 10 and 17 years. Malignancy (25.0%) was the leading cause of death, followed by pneumonia (20.8%) and sepsis (20.8%). The patient survival rate was 36.9% at 17 years after THA. Multivariate analysis exhibited that older age at operation and greater dose of concomitant corticosteroid resulted in shorter patient survivals.CONCLUSIONS:Cementless THA worked well in patients with RA. Mortality remained high among RA patients who needed THA.
DOI	10.1080/14397595.2016.1256024
PMID	27846746