YOSHIDA Atsushi
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position  
Article types Case report
Language English
Peer review Peer reviewed
Title Erosive polyarthritis caused by sepsis due to a novel species of Streptobacillus notomytis.
Journal Formal name:Modern rheumatology case reports
Abbreviation:Mod Rheumatol Case Rep
ISSN code:24725625/24725625
Domestic / ForeginForegin
Volume, Issue, Page 4(1),pp.95-98
Author and coauthor Kusuda Takeshi†*, Ryoko Asami, Yoshishige Masuda, Tanaka Masashi, Yoshida Atsushi, Kikuchi Ken, Sugihara Takahiko
Publication date 2020/01
Summary Rat-bite fever (RBF) is characterized by fever, rash and arthritis, mainly caused by Streptobacillus moniliformis. We present a case of inflammatory erosive polyarthritis with sepsis caused by Streptobacillus notomytis, a novel species isolated from S. moniliformis. A 67-year-old man presented with fever, purpura and peripheral arthritis. After blood cultures were performed, loxoprofen administration was initiated. Arthritis partially improved, but left first metatarsophalangeal (MTP) arthritis persisted. A gram-negative rod was detected in the blood culture, and meropenem administration was started that improved arthritis. Ultrasonography and computed tomography revealed bone erosion in the left first MTP joint, leading to the diagnosis of septic arthritis. 16S rRNA gene sequence analysis revealed that this strain was S. notomytis. Further questioning revealed the patient may have had contact with rats. It is essential to consider Streptobacillus infection in the differential diagnosis of erosive polyarthritis.
DOI 10.1080/24725625.2019.1655246
PMID 33086954