HANAFUSA Norio
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor
Article types Original article
Language English
Peer review Non peer reviewed
Title Granulocyte and monocyte apheresis therapy for patients with active ulcerative colitis associated with COVID-19: a case report
Journal Formal name:Intestinal research
Abbreviation:Intest Res
ISSN code:15989100/15989100
Domestic / ForeginForegin
Volume, Issue, Page 20(1),pp.150-155
Author and coauthor KOROKU Miki, OMORI Teppei*, KAMBAYASHI Harutaka, MURASUGI Shun, KURIYAMA Tomoko, IKARASHI Yuichi, YONEZAWA Maria, ARIMURA Ken, KARASAWA Kazunori, HANAFUSA, Norio, KAWANA Masatoshi, TOKUSHIGE Katsutoshi
Publication date 2022/01
Summary Coronavirus disease 2019 (COVID-19), caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is now a pandemic. Although several treatment guidelines have been proposed for patients who have both inflammatory bowel disease and COVID-19, immunosuppressive therapy is essentially not recommended, and the treatment options are limited. Even in the COVID-19 pandemic, adjuvant adsorptive granulocyte and monocyte apheresis may safely bring ulcerative colitis (UC) into remission by removing activated myeloid cells without the use of immunosuppressive therapy. Our patient was a 25-year-old Japanese male with UC and COVID-19. This is the first case report of the induction of UC remission with granulocyte and monocyte apheresis treatment for active UC associated with COVID-19.
DOI 10.5217/ir.2020.00148
PMID 33902268