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ハナフサ ノリオ
HANAFUSA, Norio
花房 規男 所属 医学部 医学科（東京女子医科大学病院） 職種 准教授 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Effectiveness of SARS-CoV-2 vaccines on hemodialysis patients in Japan: A nationwide cohort study. |
| 掲載誌名 | 正式名：Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 略 称：Ther Apher Dial ISSNコード：17449987/17449979 |
| 掲載区分 | 国外 |
| 巻・号・頁 | pp.online |
| 著者・共著者 | Kikuchi Kan, Nangaku Masaomi, Ryuzaki Munekazu, Yamakawa Tomoyuki, Yoshihiro Ota, Hanafusa Norio, Sakai Ken, Kanno Yoshihiko, Ando Ryoichi, Shinoda Toshio, Wakino Shu, Nakamoto Hidetomo, Takemoto Yoshiaki, Akizawa Tadao, |
| 発行年月 | 2022/05 |
| 概要 | INTRODUCTION:This study compared the outcomes of dialysis patients who received SARS-CoV-2 vaccine with those who did not use data from the Japanese COVID-19 registry.METHODS:A total of 1260 dialysis patients with confirmed positive SARS-CoV-2 infection was included in this study. Patients were divided into two groups: patients who experienced breakthrough infection and those who were unvaccinated. The need of oxygen supplementation and mortality risks were compared using multivariate logistic regression analysis.RESULTS:The mortality rate was 24.2% in unvaccinated patients and 8.6% in breakthrough patients. The odds ratio of need of oxygen supplementation in the breakthrough patients relative to unvaccinated patients was 0.197. The hazard ratio of mortality in the breakthrough patients relative to unvaccinated patients was 0.464.CONCLUSION:Our prospective observational study showed that SRAS-CoV-2 vaccination in hemodialysis patients is vital for reducing need of oxygen supplementation and mortality risk. |
| DOI | 10.1111/1744-9987.13887 |
| PMID | 35610734 |