HAYASHI Motohiro    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Professor
Article types	Original article
Language	English
Peer review	Peer reviewed
Title	"Donut's shape"radiosurgical treatment planning for large cystic metastatic brain tumors
Journal	Formal name：Minim Invasive Neurosurg ISSN code：14392291
Publisher	Georg Thieme Verlag KG Stuttgart
Volume, Issue, Page	54(5-6),pp.286-289
Author and coauthor	HAYASHI Motohiro†, CHERNOV Mikhail, TAMURA Manabu, IZAWA Masahiro, MURAGAKI Yoshihiro, ISEKI Hiroshi, OKADA Yoshikazu
Authorship	Lead author
Publication date	2011/10
Summary	Radiosurgical management of large cystic metastatic brain tumors represents a significant challenge. Nevertheless, modified dose planning has shown beneficial results in such cases.|"Donut's shape"radiosurgical treatment planning is based on the chain-like application of multiple, small-sized isocenters for selective coverage of the contrast-enhancing tumor capsule and minimal irradiation of the central cystic area. Such an approach was used for the management of large cystic intracranial metastases, which were not accompanied by a significant mass effect and did not require immediate volume reduction. Treatment was done using Leksell Gamma Knife model C with automatic positioning system. The majority of treated lesions showed significant shrinkage after radiosurgery and no major complications were met.|Large cystic metastatic brain tumors may be successfully treated with gamma knife radiosurgery alone using the proposed"donut's shape"dose planning with coverage of the contrast-enhancing tumor capsule by multiple small-sized isocenters.
DOI	10.1055/s-0031-1297987
Document No.	22278800