OGAWA Masaki    Department   School of Medicine(Yachiyo Medical Center), School of Medicine    Position   Professor
Article types	Case report
Language	English
Peer review	Peer reviewed
Title	Low-dose recombinant activated factor VII temporally stopped bleeding from small artery in severe postpartum hemorrhage: a case report.
Journal	Formal name：Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis Abbreviation：Blood Coagul Fibrinolysis ISSN code：09575235
Volume, Issue, Page	24(3),pp.344-6
Author and coauthor	Ogawa Masaki†*, Akahira Saeko, Takahashi Satoshi, Shimoda Yuki, Sato Megumi, Sato Akira, Terada Yukihiro
Authorship	Lead author,Corresponding author
Publication date	2013/04
Summary	Recombinant activated factor VII has been used to effectively treat uncontrolled massive hemorrhage at parturition in an off-label manner. Interventional radiology, including vessel embolization of the internal iliac artery or uterine artery for postpartum hemorrhage, is now familiar to obstetricians. However, this therapeutic technique is applicable only in patients who are hemodynamically stable. We encountered a case with severe and uncontrolled postpartum bleeding from the vaginal fornix. The patient received a low dose (<20 μg/kg) of factor VIIa and subsequently underwent vessel embolization. We herein report that this stepwise treatment was very effective for uncontrolled bleeding.
DOI	10.1097/MBC.0b013e32835975b1
Document No.	PMID: 23448730