チエルノフ　ミハイル    Department   School of Medicine(Tokyo Women's Medical University Adachi Medical Center), School of Medicine    Position   Assistant Professor
Article types	Original article
Language	English
Peer review	Peer reviewed
Title	Low-dose gamma knife radiosurgery for cavernous sinus hemangioma: report of 3 cases and literature review
Journal	Formal name：Minimally invasive neurosurgery : MIN Abbreviation：Minim Invasive Neurosurg ISSN code：09467211
Domestic / Foregin	Foregin
Publisher	Georg Thieme Verlag KG Stuttgart · New York
Volume, Issue, Page	51(3),pp.140-146
Author and coauthor	Ivanov P†, CHERNOV Mikhail, HAYASHI Motohiro, NAKAYA Kotaro, IZAWA Masahiro, TAMURA Noriko, KUBO Osami, UJIIE Hiroshi, MURAGAKI Yoshihiro, NAKAMURA Ryoichi, ISEKI Hiroshi, HORI Tomokatsu, TAKAKURA Kintomo
Publication date	2008/07
Summary	Optimal management of cavernous sinus hemangiomas remains unclear. Total microsurgical removal of these neoplasms may be extremely difficult due to their rich vascularization. Three cases of cavernous sinus hemangioma treated with low-dose Gamma Knife radiosurgery are presented. Marginal dose varied from 10 to 13 Gy. Treatment planning and radiation dosimetry were done with a goal of conformal and selective coverage of the lesion with 50% prescription isodose line using multiisocenter technique. In all cases significant shrinkage of the neoplasm was marked at 3 months after treatment. Mean volume reduction at 12 months after radiosurgery was 60% (range: 45-75%). In all patients the shrinkage of the neoplasm was accompanied by notable improvement of the preexistent oculomotor nerve palsy. No radiosurgery-related complications were met during follow-up. In conclusion, low-dose Gamma Knife radiosurgery seems to be very effective for management of cavernous sinus hemangiomas, and can be considered as a treatment modality of choice for these lesions.
DOI	10.1055/s-2008-1065346
Document No.	18521784