八巻 隆
   Department   School of Medicine(Tokyo Women's Medical University Adachi Medical Center), School of Medicine
   Position   Professor
Article types Original article
Language English
Peer review Peer reviewed
Title Prospective direct comparison study of fractional resurfacing using different fluences and densities for skin rejuvenation in Asians.
Journal Formal name:Lasers in surgery and medicine
Abbreviation:Lasers Surg Med
ISSN code:0196-8092(Print)0196-8092(Linking)
Volume, Issue, Page 39(4),pp.311-4
Author and coauthor Kono Taro, Chan Henry H, Groff William Frederick, Manstein Dieter, Sakurai Hiroyuki, Takeuchi Masaki, Yamaki Takashi, Soejima Kazutaka, Nozaki Motohiro
Authorship Corresponding author
Publication date 2007/04
Summary BACKGROUND AND OBJECTIVE:Fractional resurfacing is a new concept of cutaneous remodeling whereby laser-induced zones of microthermal injuryBACKGROUND AND OBJECTIVE:are surrounded by normal untreated tissue. The aim of this study is to compare the efficacy and complications of Fraxel laser treatment when using different fluences and density settings.STUDY DESIGN/MATERIALS AND METHODS:Thirty female Asian patients were enrolled in the study. Group 1 (n = 10); half of the face was treated with eight passes at 125 MTZ/cm2 at an energy setting of 8 mJ. The other half of the face was treated with eight passes at 250 MTZ/cm2 at an energy setting of 8 mJ. Group 2 (n = 10); half of the face was treated with eight passes at 125 MTZ/cm2 at an energy setting of 8 mJ. The other half of the face was treated with eight passes at 125 MTZ/cm2 at an energy setting of 16 mJ. Group 3 (n = 10); half of the face was treated with eight passes at 125 MTZ/cm2 at an energy setting of 16 mJ. The other half of the face was treated with eight passes at 250 MTZ/cm2 at an energy setting of 8 mJ. Ice pack cooling was used during and after laser treatment. The patients were evaluated for clinical efficacy and treatment-related side effects.RESULTS:Pain, erythema, and swelling were observed to be significantly more evident or persisted longer in patients treated with higher densities and fluences (PRESULTS:<RESULTS:0.01). Patient satisfaction is significantly greater in patients treated with higher fluences (PRESULTS:<RESULTS:0.05), but not in patients treated with higher densities. Hyperpigmentation was observed in two patients.CONCLUSION:Increased density was more likely to produce swelling, redness, and hyperpigmentation when compared to increased energy. Patient satisfaction is significantly higher when their skin is treated with high fluences, but not when patients' skin is treated with high densities.
DOI 10.1002/lsm.20484
Document No. 17457835