|
KITAJIMA Kumiko
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Assistant Professor |
|
| Article types | Original article |
| Language | English |
| Peer review | Peer reviewed |
| Title | Successful Long-term Graft Survival of a Renal Transplantation Patient with Wiskott-Aldrich Syndrome |
| Journal | Formal name：Internal medicine (Tokyo, Japan) Abbreviation：Intern Med ISSN code：09182918/13497235 |
| Domestic / Foregin | Domestic |
| Volume, Issue, Page | 55(13),pp.1761-1763 |
| Author and coauthor | KAI KOTARO†, Ogawa Yuichi, MIKI Katsuyuki, IWADOH Kazuhiro, Sannomiya Akihiro, MURAKAMI Toru, Koyama Ichiro, Kitajima Kumiko, Nakajima Ichiro, Fuchinoue Shohei |
| Publication date | 2016 |
| Summary | Wiskott-Aldrich syndrome, a rare X-linked hereditary syndrome, is characterized by immunodeficiency, thrombocytopenia, and eczema. The underlying T-cell defect renders renal transplantation and immunosuppressive treatments uncertain. The present case exhibited the mild clinical manifestation, regarded as X-linked thrombocytopenia. He successfully underwent a living-donor ABO-compatible renal transplantation and splenectomy in 2002, and thereafter experiencing no severe rejection, serious infection, or malignancy for more than 10 years. Though IgA nephropathy was detected 8 months after transplantation, the patient's renal function and proteinuria were stable without any treatment. The present case showed a successful long-term graft survival and the importance of splenectomy added to renal transplantation. |
| DOI | 10.2169/internalmedicine.55.6337 |