キタジマ　クミコ   KITAJIMA Kumiko   北島　久視子    所属   医学部 医学科（東京女子医科大学病院）    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Successful Long-term Graft Survival of a Renal Transplantation Patient with Wiskott-Aldrich Syndrome
掲載誌名	正式名：Internal medicine (Tokyo, Japan) 略　 称：Intern Med ISSNコード：09182918/13497235
掲載区分	国内
巻・号・頁	55(13),pp.1761-1763
著者・共著者	KAI KOTARO†, Ogawa Yuichi, MIKI Katsuyuki, IWADOH Kazuhiro, Sannomiya Akihiro, MURAKAMI Toru, Koyama Ichiro, Kitajima Kumiko, Nakajima Ichiro, Fuchinoue Shohei
発行年月	2016
概要	Wiskott-Aldrich syndrome, a rare X-linked hereditary syndrome, is characterized by immunodeficiency, thrombocytopenia, and eczema. The underlying T-cell defect renders renal transplantation and immunosuppressive treatments uncertain. The present case exhibited the mild clinical manifestation, regarded as X-linked thrombocytopenia. He successfully underwent a living-donor ABO-compatible renal transplantation and splenectomy in 2002, and thereafter experiencing no severe rejection, serious infection, or malignancy for more than 10 years. Though IgA nephropathy was detected 8 months after transplantation, the patient's renal function and proteinuria were stable without any treatment. The present case showed a successful long-term graft survival and the importance of splenectomy added to renal transplantation.
DOI	10.2169/internalmedicine.55.6337