KAWAMATA Takakazu
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor and Division head
Article types Other
Language English
Peer review Non peer reviewed
Title Usefulness of intraoperative magnetic resonance imaging for glioma surgery
Journal Formal name：Acta neurochirurgica. Supplement
Abbreviation：Acta Neurochir Suppl
ISSN code：00651419
Domestic / ForeginForegin
Volume, Issue, Page 98,pp.67-75
Author and coauthor MURAGAKI Yoshihiro†, MARUYAMA Takashi, KAWAMATA Takakazu, YAMANE Fumitaka, NAKAMURA Ryoichi, KUBO Osami, TAKAKURA Kintomo, HORI Tomokatsu
Publication date 2006/01/01
Summary Radical resection of gliomas can increase patient's survival. There is known concern, however, that aggressive tumour removal can result in neurological morbidity. The objective of the present study was to evaluate the usefulness of low magnetic field strength (0.3 Tesla) open intraoperative magnetic resonance imaging (iMRI) for complete resection of glioma with emphasis on functional outcome.|From 2000 to 2004, 96 patients with intracranial gliomas underwent tumour resection with the use of iMRI in Tokyo Women's Medical University. There were 50 men and 46 women; mean age was 39 years. Tumour volume varied from 1.2 ml to 198 ml (median: 36.5 mL). Resection rate and postoperative neurological status were compared between control group (46 cases, operated on during the initial period after installation of iMRI), and study group (50 most recent cases, in whom surgery was done using established treatment algorithm and improved image quality).|Overall, mean resection rate was 93%, and medial residual tumour volume was 0.17 ml. Total tumour removal was achieved in 44 cases (46%). Compared to control group, resection rate in the study group was significantly higher (91%, vs. 95%; P<0.05), whereas residual tumour volume was significantly smaller (1.7 mL vs. 0.025 mL; P<0.001). Nine patients in the control group (20%) and 24 in the study group (48%) experienced temporary postoperative neurological deterioration (P<0.01), however, the rate of permanent morbidity evaluated 3 months after surgery did not differ significantly between the groups investigated (13% vs. 14%).|Use of iMRI during surgery for intracranial gliomas permits to attain aggressive tumour resection with good functional outcome. Nevertheless, surgical experience with the iMRI system, establishment of treatment algorithm, and improvement of image quality are of paramount importance for optimal results.
DOI 10.1007/978-3-211-33303-7_10
PMID 17009703