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論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Phylogenetic relationship of Pasteurella pneumotropica isolates from laboratory rodents based on 16S rDNA sequence.
掲載誌名	正式名：The Journal of veterinary medical science / the Japanese Society of Veterinary Science 略　 称：J Vet Med Sci ISSNコード：(0916-7250)0916-7250(Linking)
巻・号・頁	68(6),pp.639-41
著者・共著者	SASAKI Hiraku, KAWAMOTO Eiichi, UESHIBA Hidehiro, AMAO Hiromi, SAWADA Takuo
発行年月	2006/06
概要	A 1344 bp fragment of the 16S ribosomal DNA (rDNA) sequence was used to determine the genetic relationship of Pasteurella pneumotropica isolates from laboratory rodents. A total of 30 nucleotide sequences of P. pneumotropica, including 24 wild strains, 3 reference strains, and 3 nucleotide sequences deposited in GenBank, were examined for heterogeneity of their 16S rDNA sequences. Phylogenetic analysis based on 16S rDNA sequence discriminated 5 types of branching lineages. Of these 5 types, 3 types had significant associations with mice or rats, and 2 had significant associations with the beta-hemolytic phenotype. These results suggest that 16S rDNA sequencing of P. pneumotropica isolates demonstrates genetic heterogeneity and phylogenetic discrimination in terms of their hemolytic phenotype and host associations.
PMID	16820726