ウエシバ ヒデヒロ
  上芝 秀博
   所属   医学部 医学科
   職種   助教
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Phylogenetic relationship of Pasteurella pneumotropica isolates from laboratory rodents based on 16S rDNA sequence.
掲載誌名 正式名:The Journal of veterinary medical science / the Japanese Society of Veterinary Science
略  称:J Vet Med Sci
ISSNコード:(0916-7250)0916-7250(Linking)
巻・号・頁 68(6),pp.639-41
著者・共著者 Sasaki Hiraku, Kawamoto Eiichi, Ueshiba Hidehiro, Amao Hiromi, Sawada Takuo
発行年月 2006/06
概要 A 1344 bp fragment of the 16S ribosomal DNA (rDNA) sequence was used to determine the genetic relationship of Pasteurella pneumotropica isolates from laboratory rodents. A total of 30 nucleotide sequences of P. pneumotropica, including 24 wild strains, 3 reference strains, and 3 nucleotide sequences deposited in GenBank, were examined for heterogeneity of their 16S rDNA sequences. Phylogenetic analysis based on 16S rDNA sequence discriminated 5 types of branching lineages. Of these 5 types, 3 types had significant associations with mice or rats, and 2 had significant associations with the beta-hemolytic phenotype. These results suggest that 16S rDNA sequencing of P. pneumotropica isolates demonstrates genetic heterogeneity and phylogenetic discrimination in terms of their hemolytic phenotype and host associations.
PMID 16820726